Brain Systems for Spatial Orientation in Health and Disease

The goal of this project is to assess impaired memory reactivation (replaying sequences of activity that were recorded during a learning task during post-task sleep) as a possible cause of impaired ability to get oriented in space we have observed in mouse models of Alzheimer's disease. Another available project is to access which normal systems in rats are responsible for spacial orientation and disrupt these systems using drugs or optogenetics (laser light inactivation).

Skills Needed: Basic science background recommended. We will teach needed skills.

Project Location: On FSU Main Campus.

  • Must be able to work 10 to 12 hours per week.
  • Flexible schedule (Combination of business and outside of business. TBD between student and research mentor.)
  • Partially Remote


  • Assist with analyzing brain recording and behavioral data for transgenic mouse models of Alzheimer's disease.
  • Assist in data collection by performing behavior experiments.
  • Section and stain brain tissue and assist with quantifying positive cells in specific brain regions.

We provide diverse, interactive, and stimulating learning opportunities by building a customized training plan that meets both the student’s and our laboratory needs. I meet students at least bi-weekly following laboratory meetings and for students with more involved training plans more often. The training is driven by the student’s interests and begins to be developed during the interview where I learn about the student’s interests and career goals and think about a good match to specific projects in my laboratory. The interview is also used to identifying students that maintain and build on the diversity in our group. Diversity leads to better ideas and solutions to problems we encounter and improves the training experience and knowledge base for everyone in my group.

Faculty Mentor(s)
Research Area

Alzheimer's disease, spatial orientation, rodent animal disease models